The science supporting

UVC technology

There is a significant body of evidence substantiating the effect of airborne pathogens on the prevalence of SSI's and HAI's.
Below is a growing body of scientific evidence showing the effectiveness of HEPA-Ultraviolet air recirculation (HUAIRS) technology. These studies range from laboratory testing, case studies, conference presentations and peer-reviewed papers.

Question 5: Is there a relationship between levels of airborne microorganisms in the (OR) and the risk of periprosthetic joint infections (PJIs)?

Recomendation: Yes, High quality evidence indicates that there is a proportional relationship between intraoperative levels of airborne microorganisms (CFU's and the incidence of PJIs.

Delegate Vote: Agree 98%, Disagree 1%, Abstain 1% (Unanimous)

Peer-reviewed Research Highlights

Reduction of PJI from 1.8% to 0% as a direct result of the use of Illuvia HUAIRS1

Cook, T., DO, Piatt, C., DO, Barnes, S., BSN, and Edmiston, Jr., C. E., PhD. The Impact of Supplemental Intraoperative Air Decontamination on the Outcome of Total Joint Arthroplasty: A Pilot Analysis. The Journal of Arthroplasty (2018)

Significantly decreased bacterial load by over 40% under routine care in an emergency department.

Bischoff, W., MD PhD, FSHEA, Russell, G., MS, Willard, E., AAS, Stehle, J., Jr. PhD. The Impact of a Novel mobile high-efficiency particulate air-ultraviolet air recirculation system on the Bacterial Air Burden during Routine Care. American Journal of Infection Control (2019).

53%-67% reduction of airborne bacterial content in active OR’s (CFU/m3 )

Parvizi, J., MS, MD, FRCS, Barnes, S., RN, CIC, Shohat, N., MD, Edmiston, C., MS, PhD. Environment of care: Is it time to reassess microbial contamination of the operating room air as a risk factor for surgical site infection in total joint arthroplasty? American Journal of Infection Control (2017).

C-UVC units significantly reduce total and viable particle counts

Curtis, G.L., MD, Faour, M., MD, Jawad, Michael, BS, Klika, MS, Barsoum, W.K., MD, Higuera, C.A., MD. Reduction of Particles in the Operating Room Using Ultraviolet Air Disinfection and Recirculation Units. The Journal of Arthroplasty (2017).

Additional  evidence 

Elevated pathogen levels in healthcare settings are a significant, yet under-appreciated cause of HAIs and SSIs.
In orthopaedic surgery, a strong correlation exists between air contamination, joint sepsis rate and the numbers of bacteria isolated from wound washout samples.
On average as many as 30% of airbourne particulates in an OR can be bacteria laden.
Research has shown that as many as 50% of surfaces remain contaminated with pathogens, including multidrug-resistant organisma such as MRSA.
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